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Very little went right for Josh Allen in a frustrating contest on Thursday evening against the Houston Texans.

And still he came close to willing the Buffalo Bills to a victory before an late pick in the final minute sealed their fate in a 23-19 loss.

The quarterback took back-to-back tackles for loss on the team's final possession, leading to a long fourth down, but the Bills (with seven wins) picked up significant yardage on a quick throw from Josh Allen to Josh Palmer, who flipped a backward pass to Khalil Shakir.

After a false-start penalty created a fourth down situation for Buffalo, a Texans defender picked off Allen’s pass at the 9-yard line with under half a minute left.

“We had a opportunity to win it there at the conclusion,” Allen said. “Our team performed a good job of hanging tough and our defense saved us a few instances. We must figure it out, and we didn’t.”

Proved tough for the signal-caller to establish rhythm on a evening he was brought down a personal-worst eight times and hit four other times. The QB threw for 253 passing yards with two interceptions and no touchdowns after producing six touchdowns in a win over Tampa Bay the previous week.

Whenever they pressure our QB 12 times, that's unacceptable,” Buffalo's head coach McDermott said. “I disapprove of that statistic at all. It’s just not a healthy way to play and it isn't a good way to keep our quarterback healthy for the rest of the season. We’ve got to play better.”

Allen was slow to rise after a sack in the first half. He said he was fine and that his left shoulder “went a little numb” after he fell on it in an awkward manner. He was questioned about being hit so many times on Thursday.

“It’s not fun,” he remarked. “I ran into a couple personally. I need to be more effective at throwing the ball away. On multiple occasions, I found myself losing ground.”

The Bills' QB lost 70 total yards on the eight sacks. Anderson had two and a half sacks to top the Texans. Another sack occurred when he nearly took Allen down near the scrimmage line, but he escaped and Anderson got up and pursued him across the field to tackle him for an 18-yard loss to force a punt in the third quarter.

The Bills played for a second straight game without wideout Keon Coleman after he was once more a non-participant after he was late to a team meeting before their previous contest. He was earlier held out for the opening drive of a loss to the Patriots in Week 5 after additionally being delayed for a meeting.

No change. We are taking it one day at a time,” McDermott noted. “I felt he had a improved week, but we’re taking it step by step. It wasn’t that it wasn’t thought about, but we opted for the guys that provide the optimal opportunity.”

Shakir led the Bills with eight receptions for 110 yards and Cook had 116 rushing yards and a touchdown.

Allen was disappointed that the Bills were unable to execute in crucial moments.

In the end, we must execute, and we didn’t succeed of that tonight,” he said. “No matter the scenario and any circumstance, we need to discover a solution, and we didn’t.”